What is Skilarence and what is it used for?
It’s a medication containing a type of medicine called a fumaric acid ester, which is used to treat moderate-to-severe plaque psoriasis in adults in need of systemic medicinal therapy. While no current treatment can completely cure your psoriasis, they may improve your signs and symptoms. Please refer to the Patient Information Leaflet on how to take your medicine.
Who should not take Skilarence?
It is suitable for adults (18 years and over) with moderate-to-severe plaque psoriasis. You should not take Skilarence if:
- You are allergic to dimethyl fumarate or any of the other ingredients in this medication (you can find the list in section 6 of the package leaflet) You have severe gastro-intestinal problems
- You have severe liver or kidney problems
- You are pregnant or breast-feeding consult your healthcare professional if you think any of these apply to you.
Is everyone given exactly the same dose of treatment?
No, after you start treatment your healthcare professional may adjust the dose to help you achieve maximum benefit and fewer side effects. The dose is individualised to each patient according to his or her needs.
What should I do if I forget to take a dose?
Do not take extra tablets to make up for a missed dose. Just wait for your next scheduled dose and carry on as normal. If you are not sure how to proceed, ask your healthcare professional or pharmacist.
Can I take Skilarence for long periods of time?
Your healthcare professional will decide, together with you, how long you should be taking your medication.
What can I do to minimise side effects?
In order to minimise side effects, you must take your tablets whole, with liquid, either during or immediately after a meal. If you’re starting Skilarence for the first time, your healthcare professional will normally start you on a low dose to begin with. This helps reduce the chance of getting side effects. Your healthcare professional will normally then gradually increase the dose depending on how well the medicine works for you, and whether it causes you any side effects. Please follow his or her advice since the dose you need may be changed to suit your needs.
Your Skilarence Planner can help you track your dosage.
Is Skilarence going to weaken my immune system?
The way Skilarence works is not fully understood, however what we do know is that it does have an effect on changing the activity of some specific types of immune cells and this can help improve the symptoms of psoriasis. The medicine works on some of the cells of the immune system (the body’s natural defences) to reduce the production of some of the substances involved in causing psoriasis. Monitoring is important to control the recommended levels of these cells in your blood.
How often should I have follow-up appointments?
Your healthcare professional will advise you on when these are required. It is important that you attend all of your appointments as requested. You should have a blood test every 3 months as a minimum.
Might my dose be reduced if I am getting side effects?
In general, most of the side effects are manageable. Your healthcare professional will increase your dose until your condition is well controlled. If you experience side effects after an increase in dose, your healthcare professional may recommend you temporarily return to the previous dose. Consult with your healthcare professional and he or she will advise on the best way of managing any side effects.
When will I see results with Skilarence?
Generally, the response to treatment may be seen as early as week 3 and normally improves over time.
Can I drink alcohol while taking Skilarence?
Avoid strong alcoholic drinks (more than 50 mL of spirits containing more than 30% alcohol by volume) during treatment with this medicine, as alcohol can interact with it. This could cause stomach and intestinal problems.
Can I take this medicine if I am lactose intolerant? Or if I have coeliac disease?
If you are lactose intolerant, ensure your healthcare professional is aware because Skilarence tablets contain lactose. Skilarence does not contain gluten, and is not contraindicated in patients with coeliac disease.
Can I take other medicines with Skilarence?
Skilarence is not known to interact with other medicines. It should only be used cautiously with other tablet or injection treatments for psoriasis and only under the supervision of your Healthcare Professional. If you experience severe or prolonged diarrhoea, absorption of other medicines may be affected. Women taking oral contraceptive medication (the Pill) may need to use other methods to prevent pregnancy because its effectiveness may be reduced. Always let your healthcare professional know which medications you are taking before starting Skilarence treatment and ask him or her before taking any other medications during treatment.
Can I take Skilarence if I am pregnant or breast-feeding?
It should not be taken during pregnancy or whilst breast-feeding. In addition, it is not recommended in women of child-bearing age who are not using contraception.
Can I drive if I am taking Skilarence?
It may have a minor influence on the ability to drive and use machines. If you feel dizzy or tired after taking Skilarence, be careful when driving or using machines.
If you have any question about the use of this medicine, ask your doctor or pharmacist.