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Are there any adverse effects?

Starting with a low dose and increasing it gradually helps reduce the likelihood and severity of gastrointestinal/stomach problems and other side effects.

You may experience some side effects during treatment although not everybody gets them.

The most common things people notice are gut-related side effects and flushing. These are usually mild, tend to appear during the first few weeks of treatment and should improve or go away as you continue treatment:

Gut-related side effects may include diarrhoea, nausea, vomiting or cramps. Other side effects not related to the gut include:

  • Flushing (reddening of the face or body)
  • Reduced white cell count (leucocytes and lymphocytes)

For the full list of adverse event please refer to the Summary of Patient Characteristics and Patient Information Leaflet accessible via the links below

Your healthcare professional will let you know when you are due for a test so you can schedule your next appointment.

Report adverse event

This website provides information to guide you during treatment with Skilarence. Please refer to the Patient Information Leaflet contained within your medicine pack for further information.

If you get any side effects, talk to your healthcare professional, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at: https://yellowcard.mhra.gov.uk/ (for United Kingdom) or by contacting the HPRA (for Ireland) at: Website: www.hpra.ie, e-mail: medsafety@hpra.ie.

By reporting side effects you can help provide more information on the safety of this medicine. Adverse events should also be reported to Almirall Ltd. IE Tel: +353 (0)14319836; UK Tel: 0800 0087 399; Email: Almirall@EU.ProPharmaGroup.com

Please read our Drug Safety Privacy Policy where you will find details of how we handle the processing of personal information when dealing with your adverse event report.

This website is intended only for patients taking Skilarence® (dimethyl fumarate) to help them maximise their treatment’s benefits. Please refer to the Patient Information Leaflet contained within the medicine pack for further information.


If you get any side effects, talk to your healthcare professional, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at: https://yellowcard.mhra.gov.uk/ (for United Kingdom) or by contacting the HPRA (for Ireland) at: Website: www.hpra.ie, e-mail: medsafety@hpra.ie. By reporting side effects you can help provide more information on the safety of this medicine.

By reporting side effects you can help provide more information on the safety of this medicine.

Adverse events should also be reported to Almirall Ltd. IE Tel: +353 (0)14319836; UK Tel: 0800 0087 399; Email: Almirall@EU.ProPharmaGroup.com